The School of Engineering is housed in the 62,000-square-foot Engineering complex. Students hone their engineering skills in computer-based classrooms and six state-of-the-art laboratories. All computers in the Engineering building were recently replaced or upgraded to the latest technology available. Testing stations exist for robotics, electromagnetics, metals fabrication, and tooling.

Additionally, the School utilizes the Science and Engineering Building as part of the Engineering complex. The facility features laboratories, specialized classrooms, a materials-testing system, study rooms, and a 150-seat auditorium. Labs in the facility include equipment and devices for students to study basic mechanical, electrical, electromagnetic, solid state, optical and nonlinear phenomena; digital and analog solid state electronic devices; the design and fabrication of devices with imbedded microprocessors; digital signal processing; and composite materials.

Located on Mercer's 130-acre Macon campus, the School of Engineering is geographically situated among the new (as of 2017) Science Building, the School of Medicine, and the Eugene W. Stetson School of Business and Economics. Mercer's College of Liberal Arts, School of Education are also in close proximity, all providing opportunities for collaboration.